Drug target discovery

Drug target discovery

Identifying antigenic targets for vaccines using traditional methods can be time-consuming.  Protein microarray is a multiplex alternative that offers significant advantages in throughput, enabling researchers to simplify screening experiments, and speed up the discovery of antigenic vaccine targets.

Watch Prof. Faith Osier talk at TED2018 about how Arrayjet's custom protein printing service helped her team to profile 10,000 human serum samples to identify antibodies against the malaria parasite, Plasmodium falciparum: The key to a better malaria vaccine

Selected publications

KILchip v1.0: A novel Plasmodium falciparum merozoite protein microarray to facilitate malaria vaccine candidate prioritization
G. Kamuyu, J. Tuju, R. Kimathi, K. Mwai, J. Mburu, N. Kibinge, M. Chong Kwan, S. Hawkings, R. Yaa, E. Chepsat, J. M. Njunge, T. Chege, F. Guleid, M. Rosenkranz, C. K. Kariuki, R. Frank, S. M. Kinyanjui, L. M. Murungi, P. Bejon, A. Färnert, K. K. A. Tetteh, J. G. Beeson, D. J. Conway, K. Marsh, J. C. Rayner and F. H. A. Osier
Frontiers in Immunology

Retrospective identification of a broad IgG repertoire differentiating patients with S. aureus skin and soft tissue infections from controls
F. Rigat, E. Bartolini, M. Dalsass, N. Kumar, S. Marchi, P. Speziale, D. Maione, L. Chen, M. R. Romano, M. Alegre, F. Bagnoli, R. S. Daum, and M. Z. David
Frontiers in Immunology


"The combination of an excellent product in their microarray printers and a responsive technical support team to assist with bespoke solutions to individual project needs were two of the many attributes that attracted us to work with Arrayjet. At every step of the design of an in-house microarray chip, we had at our disposal a dedicated team of application specialists who were very cordial and available to respond to our many queries. It was on the back of this excellent support that we eventually purchased one of their microarray printers and we have continued to enjoy excellent technical training on the instrument and engineering support."

Dr James Tuju, Principal Investigator, KEMRI Wellcome Trust, Kenya