Arrayjet Microarray Case Studies

Customer case studies

Arrayjet scientists enjoy working with customers to produce case studies that support interest in their research and further collaboration opportunities.

CDI Laboratories: the largest Human Proteome Array (HuProt™)

The largest Human Proteome Array is printed using Arrayjet inkjet technology and extensive screening services are offered via Arrayjet Advance™.

Before transferring from their traditional pin-printing technology, CDI was experiencing frequent production delays, loss-of-yield, batch inconsistency and sample waste.

Arrayjet provided an end-to-end solution, optimising each step of the CDI printing process to ensure a quality product at the end of every print run.  HuProt arrays are now used by researchers worldwide to explore:

  • Antibody specificity
  • DNA/RNA binding
  • Autoimmune profiling
  • Enzyme substrate identification
  • Small molecule profiling
  • Protein-protein interaction

Read their story here: CDI case study

HuProt™ v4.0 is now commercially available, with nearly 81% of the human proteome on a single glass slide.  Contact Arrayjet for a free quotation.

In situ protein synthesis: cost-effective and reproducible cell-free arrays

Nucleic Acid Programmable Protein Arrays (NAPPA) offer a cost-effective and highly reproducible solution to cancer and autoimmune researchers involved in biomarker profiling and drug discovery.

Manuel Fuentes' team at the Cancer Investigation Centre (Salamanca, Spain) swapped their Genetix pin-spotter for Arrayjet inkjet technology and now benefit from:

  • Tenfold reduction in sample use
  • Fivefold increase in array production
  • Fourfold increase in speed

Read the NAPPA story here: In situ protein synthesis: cost-effective and reproducible cell-free arrays

EMBL Monoclonal Antibody Core Facility: high throughput hybridoma screening

By consistently producing reliable, high quality microarrays, Arrayjet technology is assisting hybridoma screening programmes and antibody validation services, worldwide.

Prior to transferring to the Arrayjet platform, the Monoclonal Antibody Core Facility (MACF) at the European Molecular Biology Laboratory were screening hybridomas using ELISA, severely limiting the number of fusions that could be assayed per week.  By transferring their technology, the MACF benefitted from:

  • Threefold reduction in weekly sample and slide costs
  • Automated print run, enabling staff remained available for other projects
  • Speed enabled eight hybridoma fusions to be screened every week

Read their story here: High throughput hybridoma screening by microarray: case study

Inkjet printing for the production of protein microarrays

The ability of Arrayjet technology to print viscous samples in viscous cryoprotectant solutions such as glycerol or ethylene glycol is a distinct advantage.  That the print head never comes into contact with the slides is essential for printing protein microarrays on delicate nitrocellulose or hydrogel surfaces.

In providing the most high throughput technology, Arrayjet enable researchers to quickly produce multiplex arrays for commercial screening, validation or diagnostic purposes.

Read Arrayjet's peer-reviewed article here: Inkjet printing for the production of protein microarrays