Arrayjet Case Studies
In this section
Arrayjet scientists work closely with customers to ensure all aspects of their application are optimised.
Over time, a selection of case studies will be released detailing how Arrayjet technology has improved productivity for researchers, worldwide
CDI Laboratories: the largest Human Proteome Array (HuProt™)
The largest Human Proteome Array (CDI's HuProt™) is printed with Arrayjet inkjet bio-printing technology.
Before transferring from their traditional pin-printing technology, CDI were experiencing frequent production delays, loss of yield, batch inconsistency and sample waste.
Arrayjet provided an end-to-end solution, optimising each step of the CDI printing process to ensure a quality product at the end of every print run. CDI HuProt arrays are now used by researchers worldwide to explore:
- Antibody specificity
- DNA/RNA binding
- Autoimmune profiling
- Enzyme substrate identification
- Small molecule profiling
- Protein-protein interaction
Read their story here: CDI HuProt™: case study
HuProt™ v3.0 is now commercially available, with nearly 75% of the human proteome on a single glass slide: HuProt™ v3.0
In situ protein synthesis: cost-effective and reproducible cell-free arrays
Nucleic Acid Programmable Protein Arrays (NAPPA) offer a cost-effective and highly reproducible solution to cancer and autoimmune researchers involved in biomarker profiling and drug discovery.
Manuel Fuentes' team at the Cancer Investigation Centre (Salamanca, Spain) swapped their Genetix pin-spotter for Arrayjet inkjet technology and now benefit from:
- Tenfold reduction in sample use
- Fivefold increase in array production
- Fourfold increase in speed
Read the NAPPA story here: In situ protein synthesis: cost-effective and reproducible cell-free arrays
EMBL Monoclonal Antibody Core Facility: high throughput hybridoma screening
By consistently producing reliable, high quality microarrays, Arrayjet technology is assisting hybridoma screening programmes and antibody validation services, worldwide.
Prior to transferring to the Arrayjet platform, the Monoclonal Antibody Core Facility (MACF) at the European Molecular Biology Laboratory were screening hybridomas using ELISA, severely limiting the number of fusions that could be assayed per week. By transferring their technology, the MACF benefitted from:
- Threefold reduction in weekly sample and slide costs
- Automated print run, enabling staff remained available for other projects
- Speed enabled eight hybridoma fusions to be screened every week
Read their story here: High throughput hybridoma screening by microarray: case study
Inkjet printing for the production of protein microarrays
The ability of Arrayjet technology to print viscous samples in viscous cryoprotectant solutions such as glycerol or ethylene glycol is a distinct advantage. That the print head never comes into contact with the slides is essential for printing protein microarrays on delicate nitrocellulose or hydrogel surfaces.
In providing the most high throughput technology, Arrayjet enable researchers to quickly produce multiplex arrays for commercial screening, validation or diagnostic purposes.
Read Arrayjet's peer-reviewed article here: Inkjet printing for the production of protein microarrays